EO detection spectrometer, especially the model based on gas chromatography technology, integrates precise injection system, efficient chromatographic separation column, high-sensitivity detector and advanced data processing system to form a complete and efficient analysis process. Its core lies in the precise quantitative analysis capability, which can accurately measure the residual concentration of EO in the sample and provide reliable data support for product quality control.
Injection system: The injection system of EO detection spectrometer usually adopts automatic sample injector or manual injection needle to ensure that the sample can enter the vaporization chamber accurately and quickly. The vaporization chamber usually has constant temperature and rapid heating functions, so that the sample can be completely vaporized in a short time, providing stable sample vapor for subsequent chromatographic separation.
Chromatographic separation column: The chromatographic separation column is one of the core components of EO detection spectrometer. It uses the distribution difference between different compounds in the stationary phase and the mobile phase to achieve sample separation. EO detection spectrometer usually uses capillary chromatographic column, which has the advantages of high separation efficiency, high resolution and low sample consumption.
Detector: Common detectors used in EO detection spectrometers include flame ionization detector (FID), electron capture detector (ECD) and mass spectrometer (MS). These detectors can convert EO components in the sample into electrical signals, and the intensity of the signal is proportional to the concentration of EO. By measuring the intensity of the electrical signal, quantitative analysis of EO residue can be achieved.
Data processing system: The data processing system of the EO detection spectrometer usually includes functions such as data acquisition, processing, analysis and reporting. It can automatically collect the electrical signal output by the detector, perform filtering, baseline correction, peak identification and other processing, and finally output the quantitative results of EO residue.
Quantitative analysis of EO detection spectrometers usually adopts external standard method or internal standard method. The external standard method is to establish a linear relationship between the response value and the concentration by measuring the response value of a standard of known concentration under the same conditions, and then use this linear relationship to calculate the concentration of the unknown sample. The internal standard method is to calculate the concentration of the component to be measured by adding an internal standard of known concentration to the sample and using the ratio of the relative retention time and response value of the internal standard to the component to be measured on the chromatographic column. Both methods can provide accurate quantitative results to meet the needs of product quality control.
The precise quantitative data provided by the EO detection spectrometer provides a solid scientific basis for product quality control. During the production process, companies can regularly test the products for EO residues to ensure that each batch of products meets the established quality standards and safety requirements.
In order to ensure product quality, companies need to regularly test the products for EO residues during the production process. This includes raw material testing, intermediate product testing, finished product testing, and stability testing. Through regular testing, companies can promptly discover and correct problems in the production process to ensure that product quality is always under control.
The control standards for EO residues vary depending on product type, use, and target market. For example, in the pharmaceutical industry, the control standards for EO residues are usually stricter for medical devices and drug packaging materials that come into direct contact with the human body. In the food industry, the control standards for EO residues are also relatively high for food packaging materials that are directly consumed. Therefore, when formulating quality control standards, companies need to fully consider the product type, use, and regulatory requirements of the target market to ensure that the products meet the relevant standards.
As people pay more and more attention to product safety, governments and relevant agencies around the world are increasingly strict in regulating EO residues. Enterprises need to pay close attention to changes in relevant domestic and foreign regulations to ensure that products meet the latest regulatory requirements. The precise quantitative data provided by the EO detection spectrometer provides strong support for enterprises to comply with regulations.
Take a medical device manufacturer as an example. The medical devices produced by the company use EO during the sterilization process. In order to ensure product quality and safety, the company introduced an EO detection spectrometer for EO residue detection. Through regular testing, the company found that the EO residue of a batch of products exceeded the established quality standards. After analysis, the company found that it was caused by improper sterilization parameter settings. Subsequently, the company adjusted the sterilization parameters and re-tested the EO residue. The results showed that the EO residue of the adjusted product met the quality standards. This case fully demonstrates the important role of EO detection spectrometers in product quality control.