In EO gasification system, the concentration and purity of EO gas are the key to achieve efficient sterilization effect. Too low concentration means that EO molecules are unevenly distributed or insufficient in number in the sterilization chamber, making it difficult to fully contact and react with microorganisms, resulting in incomplete sterilization and affecting the sterilization effect. On the contrary, too high concentration may bring a series of problems. Too high EO concentration will increase the amount of residues in sterilized items, which not only requires additional processing steps to remove the residues, but also may pose a potential threat to the environment and human health. High concentration of EO gas may produce more harmful gases such as carbon dioxide and nitrogen oxides during the sterilization process, further aggravating environmental pollution.

The purity of EO gas also directly affects its sterilization effect. The presence of impurities may interfere with the reaction between EO and microbial biomolecules and reduce the sterilization efficiency. For example, if EO gas contains moisture, oxygen or other volatile organic matter, these impurities may compete with EO for the reaction sites on the surface of microorganisms, thereby weakening the sterilization effect of EO. Impurities may also promote the decomposition of EO, produce toxic byproducts, and cause greater harm to the environment and human health.

In order to ensure the concentration and purity of EO gas in the EO gasification system, it is necessary to take comprehensive measures from multiple aspects.

Gasification is the key step for EO to be converted from liquid to gas. During the gasification process, it is necessary to accurately control parameters such as heating temperature, gasification rate, and pressure in the gasification chamber to ensure that EO gas can be generated evenly and stably. Too high or too low heating temperature may affect the concentration and purity of EO gas. Therefore, the gasification system is usually equipped with advanced temperature control systems and pressure sensors to achieve accurate monitoring and adjustment of the gasification process.

The gasified EO gas may contain trace impurities such as moisture, oxygen, nitrogen, and incompletely gasified EO liquid. These impurities need to be removed by efficient separation and purification devices. Common separation methods include condensation, adsorption, and membrane separation. The condensation method uses the difference in solubility of different substances at different temperatures for separation; the adsorption method uses the adsorption of impurities by adsorbents to remove them; and membrane separation uses the selective permeability of the membrane to separate impurities. By choosing the right separation and purification method, the purity of EO gas can be effectively improved.

To ensure that the concentration and purity of EO gas are always within the ideal range, the gasification system also needs to be equipped with real-time monitoring and feedback control devices. These devices can detect the concentration and purity of EO gas in real time, and automatically adjust the parameters in the gasification process, such as heating temperature, gasification rate, etc., according to the test results, to achieve precise control of the concentration and purity of EO gas. At the same time, these devices can also issue alarms in time to remind operators to pay attention to potential problems and take corresponding measures.

In addition to precise control of the gasification process, it is also necessary to optimize the sterilization process parameters according to factors such as the characteristics of the sterilized items, sterilization requirements and environmental conditions. For example, the sterilization effect can be improved and the residual risk can be reduced by adjusting parameters such as temperature, humidity, pressure, and EO gas concentration and exposure time in the sterilization chamber. At the same time, pre-vacuum treatment, post-treatment and other measures can be used to further reduce the residual amount.

The performance and stability of the gasification system are crucial to ensure the concentration and purity of EO gas. Therefore, the gasification system needs to be maintained and calibrated regularly. This includes cleaning the residues in the gasification chamber, replacing aged seals and filters, calibrating sensors and controllers, etc. Regular maintenance and calibration can keep the gasification system in good condition, ensure its long-term stable operation and meet the sterilization requirements.

In order to improve the sterilization effect of its EO sterilization equipment and reduce the residual risk, a medical device company improved the gasification system. They first upgraded the temperature control system and pressure sensor in the gasification process to achieve accurate monitoring and adjustment of the gasification process. They introduced efficient separation and purification devices and real-time monitoring and feedback control devices to further improve the purity and concentration stability of EO gas. In addition, they optimized the sterilization process parameters according to the characteristics of the sterilized items, and regularly maintained and calibrated the gasification system. Through these improvement measures, the company successfully improved the sterilization effect of EO sterilization equipment and reduced the residual risk.